IDENTIFYING FUNCTIONAL NETWORK CHANGING PATTERNS IN INDIVIDUALS AT CLINICAL HIGH-RISK FOR PSYCHOSIS AND PATIENTS WITH EARLY ILLNESS SCHIZOPHRENIA: A GROUP ICA STUDY

Identifying functional network changing patterns in individuals at clinical high-risk for psychosis and patients with early illness schizophrenia: A group ICA study

Although individuals at clinical high risk (CHR) for psychosis exhibit a psychosis-risk syndrome involving attenuated forms of the positive symptoms typical of schizophrenia (SZ), it remains unclear whether their resting-state brain intrinsic functional networks (INs) show attenuated or qualitatively distinct patterns of functional dysconnectivity

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DETERMINANTS OF THE DEVELOPMENT OF FAMILY FARMS BREEDING ANIMALS OF CONSERVATIVE BREEDS IN CONDITIONS OF SUSTAINABLE AGRICULTURE

The aim of the research was to determine the role and significance of natural, economic and social conditions influencing the development of family farms keeping animals of conservative breeds in conditions of sustainable agriculture.Family farms are conducive to the sustainable development of agriculture, particularly in farms which keep animals o

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Targeting active RAS with molecular glue

Activating mutations in RAS genes, notably KRASG12C, are pervasive in numerous aptamil allerpro cancers, presenting formidable challenges to therapy due to their elusive druggability.The landmark discovery of KRASG12C allosteric inhibitors marked a transformative milestone in cancer treatment, resulting in the approval of sotorasib and adagrasib.Ho

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